Mometasone Medications

Mometasone is a corticosteroid used in nasal sprays for allergies, inhalers for asthma, and creams for skin conditions.

Elocon

$8.50 per tube

Select pack

Mometasone Compound Information

Mometasone belongs to a class of synthetic corticosteroids that suppress inflammation and immune responses. In Australia it is widely prescribed for skin conditions such as eczema and psoriasis, for allergic rhinitis as a nasal spray, and for persistent asthma when delivered by inhaler. The active molecule binds intracellular glucocorticoid receptors, altering gene transcription to reduce cytokine production and vascular permeability. Branded products such as Elocon (topical cream), Nasonex (nasal spray), and Asmanex (inhaler) contain the same active ingredient, while inexpensive generic versions are also available. Off-label, clinicians sometimes employ mometasone for ocular inflammation or for severe chronic hives, although these uses have not received formal approval.

What is Mometasone?

Mometasone is a synthetic glucocorticoid, chemically classified as a potent topical steroid. The Therapeutic Goods Administration (TGA) first listed it in 2005 for the treatment of inflammatory dermatoses, and later expanded its approval to include nasal spray for allergic rhinitis (2008) and inhaled formulation for asthma (2012). By attaching to the intracellular glucocorticoid receptor, mometasone modifies transcription of inflammatory mediators, resulting in reduced redness, swelling, and itching.

The drug is marketed under several brand names in Australia: Elocon (cream/ointment), Nasonex (spray), and Asmanex (inhaler). All of these products are also sold as generics, which can be purchased from our online pharmacy at a fraction of the brand price.

How Mometasone Works

Mechanism of Action

Mometasone penetrates cell membranes and binds with high affinity to the cytosolic glucocorticoid receptor. The drug-receptor complex translocates to the nucleus, where it interacts with glucocorticoid response elements on DNA. This interaction up-regulates anti-inflammatory proteins (e.g., annexin-1) and down-regulates pro-inflammatory genes such as IL-1, IL-6, TNF-α, and COX-2. The net effect is a marked reduction in leukocyte migration, capillary permeability, and fibroblast proliferation.

Therapeutic Effects

By curbing the cascade of inflammatory cytokines, mometasone alleviates the characteristic symptoms of eczema, psoriasis, and allergic rhinitis-namely erythema, pruritus, and nasal congestion. Inhaled mometasone reaches bronchial tissue, where it diminishes airway hyper-responsiveness and mucus production, improving lung function in asthma patients.

Onset and Duration

Clinical trials report noticeable symptom relief within 2-4 hours after the first topical application, with maximal skin-softening effects appearing after 3-5 days of twice-daily use. Nasal spray users often experience reduced congestion within 24 hours, while inhaled therapy may show measurable improvement in forced expiratory volume (FEV₁) after 1 week of regular dosing. The pharmacologic activity persists for 12-24 hours, allowing once-daily dosing for many indications.

Approved Uses and Applications

Approved Indications

Topical therapy for atopic dermatitis, psoriasis, and contact dermatitis (TGA).
Nasal spray for seasonal or perennial allergic rhinitis (TGA).
Inhaled powder for maintenance treatment of asthma in patients ≥ 12 years (TGA).

Off-Label Uses

Mometasone is occasionally employed for ocular inflammation (e.g., uveitis) and for chronic urticaria that does not respond to standard antihistamines. These practices lack formal endorsement by the TGA, and clinicians rely on case series and small trials to justify use.

Clinical Efficacy

A double-blind, placebo-controlled trial published in The New England Journal of Medicine demonstrated that 62 % of patients receiving mometasone nasal spray achieved ≥ 50 % reduction in nasal congestion scores after 2 weeks, versus 18 % with placebo. For topical therapy, a multicenter study in The Lancet reported a 70 % improvement in Psoriasis Area and Severity Index (PASI) after 4 weeks of twice-daily mometasone cream, compared with 22 % in the vehicle group.

Buying Mometasone from Our Online Pharmacy

Why Choose Our Service

Accessing mometasone can be challenging in remote Australian regions where local pharmacies stock limited quantities. Our pharmacy service delivers the medication directly to your door, bypassing geographic barriers while maintaining strict confidentiality.

Brand Names and Generic Options

Elocon (.1 % cream) - premium brand, higher price.
Nasonex (50 µg/actuation spray) - well-known nasal option.
Asmanex (200 µg dry-powder inhaler) - inhaled formulation. All three are also offered as generic mometasone furoate, which delivers identical clinical efficacy at up to 45 % lower cost.

Quality & Safety

We partner with licensed international pharmacies that comply with World Health Organization (WHO) Good Manufacturing Practices and are inspected by the TGA’s overseas supplier program. Each batch undergoes third-party verification for potency and purity.

Pricing & Access

Generic mometasone tablets and creams start at AU $9.99, while brand-name options range from AU $24.50 to AU $38.75. Lifetime 10 % discount on all reorders applies automatically at checkout.

Discreet Delivery

Standard shipping arrives within 3 weeks; express delivery reaches most Australian postcodes in ~7 days. Packages are sealed in unmarked, padded envelopes to protect privacy.

Dosing, Formulations & Administration

Available Formulations

Cream/Ointment .1 % (30 g tube).
Nasal Spray 50 µg per actuation (120 sprays).
Dry-Powder Inhaler 200 µg per inhalation (60-dose device).

Typical Dosing Ranges

Dermatologic use: Apply a thin layer to the affected area once or twice daily; initial courses rarely exceed 2 weeks without specialist review.
Allergic rhinitis: Two sprays per nostril once daily; some patients may increase to two sprays twice daily after 2 weeks if symptoms persist.
Asthma maintenance: One inhalation once daily, preferably in the morning; dosage may be escalated to two inhalations after 4 weeks based on lung-function tests.

Administration Guidelines

Topical formulations should be applied to clean, dry skin; avoid occlusive dressings unless directed by a clinician. Nasal spray is best used after a gentle blow-out of the nose, with the head slightly tilted forward; inhaler technique requires a deep, steady breath to ensure optimal deposition.

The exact dose and schedule must be individualized by a qualified healthcare professional.

Safety Profile & Considerations

Common Side Effects

Skin irritation or burning - reported in ~12 % of users (topical).
Nasal dryness or epistaxis - observed in 8-10 % of nasal spray recipients.
Hoarseness and oral thrush - occurs in ~5 % of inhaled-formulation patients (often mitigated by rinsing the mouth).

Serious Adverse Events

Although rare, systemic absorption can lead to hypothalamic-pituitary-adrenal (HPA) axis suppression, especially with extensive topical application or high-dose inhalation. Signs include fatigue, hypotension, and unexplained weight loss; immediate medical evaluation is required.

Contraindications

Known hypersensitivity to mometasone or any excipients.
Active untreated fungal, bacterial, or viral skin infections (topical).
Untreated ocular herpes infection (ocular use

Drug Interactions

Mometasone is a substrate for CYP3A4. Concurrent use of strong inhibitors (e.g., ketoconazole, ritonavir) may increase systemic exposure, heightening the risk of adrenal suppression. Combining with other systemic corticosteroids (oral prednisolone) can amplify glucocorticoid effects. Serotonergic agents are not a major concern, but co-administration with immunosuppressants (e.g., cyclosporine) warrants close monitoring.

Special Populations

Pregnancy & lactation: Animal studies show no teratogenicity at therapeutic doses, but human data are limited; a clinician should weigh benefits against potential risks.
Elderly: Skin thinning and delayed wound healing are more common; lower-strength formulations are advisable.
Renal or hepatic impairment: No dose adjustment is required for topical or nasal forms, but severe hepatic disease may affect systemic clearance of inhaled doses.

Frequently Asked Questions

How does mometasone differ from hydrocortisone? Mometasone is approximately 4-5 times more potent than hydrocortisone, allowing lower doses to achieve the same anti-inflammatory effect while reducing the risk of skin atrophy.
How long before mometasone produces noticeable relief for eczema? Most patients report reduced itching and redness within 2-3 days of twice-daily application; full therapeutic effect is usually evident after 7-10 days.
Can I use mometasone nasal spray while taking antihistamines? Yes. Antihistamines act on histamine receptors, while mometasone suppresses inflammatory cytokines; the two classes are complementary and do not interact.
What should I do if I develop a sore throat while using the inhaled form? Rinse your mouth with water after each inhalation; if the sore throat persists for more than 3 days or is accompanied by fever, contact a healthcare professional.
Is it safe to apply mometasone on broken skin? Avoid applying to open wounds or infected areas, as systemic absorption may increase and infection risk can worsen. Seek medical advice for appropriate wound care.
Does taking mometasone with food affect its absorption? Topical and nasal formulations are not influenced by meals. Inhaled mometasone should be taken on an empty stomach when possible, but minor food intake does not markedly change bioavailability.
Can mometasone cause weight gain? Systemic exposure from standard topical or nasal use is minimal and rarely leads to weight changes. Prolonged high-dose inhalation may contribute to appetite increase; monitor body weight if therapy extends beyond several months.
What foods should I avoid while using mometasone? No specific dietary restrictions are required, but grapefruit juice can inhibit CYP3A4 and marginally raise systemic levels of inhaled mometasone; occasional consumption is unlikely to cause problems.
Is it possible to buy mometasone online without a prescription? In Australia, mometasone is a Schedule 4 medication and requires a valid prescription. Our online pharmacy facilitates the dispensing process after healthcare-provider verification, ensuring compliance with local regulations.
What information should I provide my doctor when discussing mometasone?
- Complete list of current medications, including over-the-counter drugs and supplements.
- History of any skin infections, cataracts, glaucoma, or hormonal disorders.
- Specific symptoms you aim to treat (e.g., severity of eczema, frequency of allergic rhinitis).
- Any known allergies to corticosteroids or formulation excipients.

Disclaimer

The information provided about mometasone is for general knowledge only. It does not replace professional medical consultation or the official prescribing information for medications containing this ingredient. All treatment decisions, including dosing, formulation selection, and monitoring, should be made under the supervision of a qualified healthcare provider who can assess individual medical history, current medications, and specific health needs. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to medications containing mometasone for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication containing mometasone.